フロー反応例 - Syrris

アジア　フローケミストリの実施例

シリカサポートPd触媒を用いた鈴木反応

• より早い反応と選択性
• きわめて少量のPdレベル

Hantzsch pyrrole 合成

• 高速反応と収率の向上
• ワンステッププロセス

ゴールドナノパーティクル合成

• 狭い粒度分布幅
• 安全な腐食性薬品利用

N-alkylation of a primary anime

• 高速反応と優れた mono-alkylationの選択性

For examples of flow chemistry performed on Syrris equipment and published in peer reviewed journals please click here.

The list below shows some of the reactions that have been performed on Syrris flow chemistry systems.

Homogeneous catalysis

• Suzuki reaction
• Heck reaction
• Grubbs metathesis

Multicomponent reactions

• Passerini 3CR
• Biginelli 3CR
• Ugi 4CR

Deprotection chemistry

• BOC deprotection
• MOM deprotection and intra epoxide opening
• Ester saponification

Ring formations

• Grubbs metathesis
• Ugi followed by ring closure
• Diels Alder
• 1,3,4 Oxadiazole formation
• Fischer indole synthesis
• 1,3 Thioamidozole formation

Oxidations and reductions

• Borohydride reduction
• Borane reduction of a heterocycle
• Reductive amination
• Dess Martin alcohol oxidation

General syntheses

• Aldol reaction
• Biphasic Schotten-Baumann
• HBTU amide coupling
• Elimination of an alcohol to alkene
• Esterification of an alcohol
• Wittig reaction
• Nucleophilic aromatic substitution
• SN1 reaction
• Mitsunobu reaction